A field experiment was conducted during 2008 to 2009 cropping season at Panchbibi upazilla of Joypurhat district in Bangladesh to study the productivity of sugarcane with five selected winter crops as first and sesame as second intercrop in paired row planting system under Tista Meander flood plain soils of Bangladesh. Five different winter crops namely, lentil, onion, mustard, potato, garlic as first intercrops followed by sesame as second intercrop were grown with sugarcane variety Isd 26. The highest tiller (212.49*10 -3 ha -1), highest millable cane (108.32*10 -3 ha -1) and highest cane yield (103.98 t ha -1) were obtained in T5 (T1+Potato-sesame) treatment. The highest second intercrop sesame yield found in T4 (T1+Mustard-sesame) treatment (0.44 t ha -1). The highest equivalent cane yield was as intercrop (82.09 t ha -1) and the highest total adjusted cane yield (186.07 t ha -1) were found in T5 (T1+Potato-sesame). The highest Brix (%) was obtained in T1 (paired row cane) treatment (20.30%). The highest total production cost T5 (T1+Potato-sesame) treatment (Tk. 95,000.00 ha -1). The highest gross return and highest gross margin were obtain in T5 (T1+Potato-sesame) treatment (Tk. 3,28,971.76 ha -1) and (Tk. 2,33,971.76 ha -1), respectively. The highest benefit cost ratio (3.46) was found in T5 (T1+Potato-sesame) treatment and lowest (2.38) in T1 (paired row cane only) treatment. It is concluded that the potato as first and sesame as the second intercrop grown in paired row transplanted sugarcane seems to be profitable intercropping combinations for sugarcane farming.