Two independent experiments were established in a Red Yellow Argisol Cambic soil objecting to evaluate potato yield and tuber size distribution profile in response to interplant spacing and fertilizer recommendation criteria. One experiment was sprinkler irrigated and the other one was drip-irrigated. Six treatments resulting from the combination of three interplant spacing (29, 36, and 50 cm) and two fertilizer recommendation criteria (by area or by plant number in the area) were evaluated in a completely randomized block design and five replications. In both experiments, marketable potato yield (tuber number and mass) exponentially decreased with the increase in row spacing and it was affected by recommendation criteria. The combination of fertilizer recommendation by area with narrower space optimizes marketable tuber yield by increasing medium and small tubers and also increases fertilizer use efficiency. Environmental, economic and practical implications of the results to potato production are discussed.