Poor use efficiency of phosphorus is one of the major causes to lower the yield of wheat crop. Time and method of P 2O 5 application influence the degree of responsiveness. Therefore, an investigation was carried out under field conditions to compare three times (pre-plant, at 1st irrigation and at 2nd irrigation) and two methods (broad cast and placement) of P 2O 5 applications for wheat grown in three cropping zones (central, cotton and thal zone) of Punjab province of Pakistan. The division of zones is based on agro-climatic conditions and cropping pattern followed by the farmers. The hypothesis was made to suggest best time and method of P 2O 5 application in order to enhance its use efficiency. The experiments were chalked out by applying recommended dose of N, P 2O 5 and K 2O @160, 114 and 62 Kg ha -1in all treatments except control throughout study. The sources of N, P 2O 5 & K 2O were Urea, Single Super Phosphate (SSP) and Sulphtate of Potash (SOP). Three, nine and one field trials were conducted during 2008-09 at framer's fields in central, cotton and thal cropping zones of the Punjab province, respectively. It was found that time and method of P 2O 5 application significantly ( P