Soil-applied herbicides are commonly used for broad-spectrum residual weed control in Florida citrus. Groundwater contamination from some soil-applied herbicides has been reported in citrus growing areas in Florida. Indaziflam is a new soil-applied herbicide recently registered for broad-spectrum weed control in Florida citrus. There is no information available on leaching behavior of indaziflam in sandy soil. Experiments were conducted to compare leaching of indaziflam with five commercially used residual herbicides in a Florida Candler soil under simulated rainfall of 5 or 15 cm ha -1. Herbicide movement down soil columns was measured by visually evaluating injury and harvesting aboveground biomass of the bioassay species annual ryegrass. Ryegrass was not injured and plant biomass was not affected beyond 30 cm when indaziflam at a recommended rate of 73 g ai ha -1 was leached through the soil column. Leaching of indaziflam increased with increasing amounts of rainfall. For example, indaziflam leached up to 12.20.8 cm (values are expressedSD) and 27.22.6 cm at 5 and 15 cm ha -1 rainfall, respectively. The herbicide ranking from high to low mobility at 15 cm ha -1 of rainfall was bromacil=norflurazon>indaziflam>simazine=pendimethalin>diuron. Overall results suggested that indaziflam leaching was limited in Florida Candler soil in this study; however, field experiments are required to confirm the leaching of indaziflam under natural rainfall situation.