Field experiment was conducted at Cotton Research Station, Srivilliputtur during 2005-2008 to study the response of summer irrigated cotton to the preceding crop, residue management and INM practices. The results revealed that maize as a preceding crop was advantageous with its stalk incorporated with the highest seed cotton yield of 1573 kg/ha and was comparable with maize as a preceding crop with stalk removed. With regard to INM practices, application of 100 per cent RD of fertilizers+azophos registered the highest seed cotton yield and was comparable with 75 per cent RD of fertilizers+azophos, 100 per cent RD of fertilizers+FYM and 100 per cent RD of fertilizers alone indicating that 75 per cent RD of fertilizers+azophos was optimum to get economic yield.