In the southeastern USA, winter rape in addition to winter wheat can become another commercial crop with benefits such as breaking of disease and insect cycles caused by continuous wheat cropping. Information on agronomic production practices and comparative profitability of rape and wheat for the southeastern USA is lacking. Therefore, from 1998 to 2005, a series of field experiments were conducted on rape to determine the optimum planting date, seeding, nitrogen and sulfur rates, rotation suitability with summer crops and comparative economic value to winter wheat. Results from three planting dates, three seeding rates and four nitrogen rates experiments showed that rape planted in early October produced significantly higher seed yield (3204 kg/ha) than from mid to late October 10-15 (2362 and 2058 kg/ha) plantings. The seeding rate of 6.0 kg/ha and 180 kg N/ha gave the highest (3779 kg/ha) seed yield. Rape response to sulfur application was significant and highest seed yield (3259 kg/ha) was obtained with 30 kg S/ha along with 228 kg N/ha. As a rotation crop after soyabean and maize, rape gave significantly higher yields of 3129 and 2938 kg/ha, respectively, than when planted after cotton (2521 kg/ha) or grain sorghum (2650 kg/ha). Both winter rape and wheat produced similar yields of 2.6 and 2.9 t/ha, respectively. As grain crop, canola with its higher price fetched $220/ha compared to $109/ha from wheat, however, this profitability is almost equal when income from wheat straw was added to that from grain.