In spite of potential benefits and positive assessments of reducing primary tillage operations, only a small part of irrigated row crops is currently managed using reduced tillage, for reasons that include concerns about its agronomic suitability for certain crop rotations. Three years of a tomato/corn rotation under standard and no-tillage management were used to understand the fate of a fertilizer and cover crop nitrogen (N) application. Uptake of both inputs was reduced under no-tillage during the year of application, in this case a tomato crop. As a result, more input N was retained in the soil in this system. The initial challenge of reduced tomato yields diminished as no-tillage management remained in place and the soil N reservoir developed. Corn production was not affected by tillage treatment. Inclusion of a legume cover crop increased the amount of fertilizer N retained in the soil over time, more so under no-tillage than under standard tillage, emphasizing the benefit of cover crops in reducing the amount of fertilizer required to maintain productivity. While acceptance of reduced tillage ultimately depends on economic performance, the results of this study support its agronomic viability for irrigated row crops.