A field experiment was conducted during 2001-02 to 2005-06 to assess the nutrients utilization and their translocation to grains in various cropping systems. The soil was sandy loam in texture and medium in soil fertility. Seven cropping systems viz. pearlmillet-wheat, pearlmillet-mustard, soybean-wheat-cowpea (f), sorghum (f)-wheat, pearlmillet-potato-green gram, pearlmillet-field pea-maize (f) and cotton-wheat were grown. In general the total nitrogen (N) uptake was higher with 3 crops in a year as compared to 2 crops in a year. The results revealed that the N uptake was highest in soybean-wheat-cowpea (f) cropping system while phosphorus (P) and potassium (K) uptake were highest in pearlmillet-potato-green gram cropping system. During kharif, the highest per cent translocation of N and P to grains was observed in soybean and K in cotton. The translocation percentage of N and P to grains was highest in wheat in sorghum (f)-wheat, and soybean-wheat-cowpea (f) cropping systems, respectively; and K in potato in rabi.