A field experiment was conducted during Kharif 2007 and summer 2008 on sandy loam soil of Hebbal, Bangalore, University of Agricultural Sciences, Bangalore, to know the comparative performance of tank mix application of chlorimuron ethyl (Kloben 25% WP)+quizalofop-p-terfuryl (Pantera 4% EC) on controlling weeds in soybean and seed yield Tank mix combination of chlorimuron ethyl 9 g+quizalofop-p-tefuryl 40 g ai/ha -20 DAS with surfactant (1598 kg/ha) or without surfactant (1518 kg/ha) gave seed yield similar to hand weeding twice (1720 kg/ha), as result of good control of grasses, broad leaf weeds and sedge. Unweeded control lowered the yield by 61% mainly due to severe competition offered by grasses. Thus, use of chlorimuron ethyl 9 g+quizalofop-p-terfuryl 40 g ai/ha+0.2% surfactant (as tank mix) at 20 DAS can be used safely for broad spectrum weed control in irrigated soybean.